Case Studies

From fractured to functional.

A selection of recent work across genomics, diagnostics, and clinical lab platforms.

Hands sketching a workflow diagram with connected boxes and arrows, mapping a complex system on paper

Case 01

Defined MVP in 60 days across a fractured team

Aligned architecture and stakeholders for a complex sequencing platform.

A next-generation sequencing platform entered development without alignment across hardware, software, bioinformatics, and operations. Led end-to-end system architecture and workflow definition to align cross-functional teams and protect the MVP timeline.

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Outcomes

Aligned 18+ product-defining architecture decisions
Defined 16 features to mitigate assay failure and user error
Descoped 11 non-critical features to reduce cost and complexity

Case 02

10x throughput, no added headcount

Re-architected workflow for single-operator execution; 96 → 960/week.

A CAP/CLIA clinical lab needed to scale Sanger sequencing without adding headcount. The existing automation redistributed complexity rather than reducing it. Redesigned the workflow end-to-end for robustness, auditability, and operator efficiency.

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Outcomes

Scaled throughput from 96 samples/week to 192 samples/day
Reduced CLS time from ~2 hours to 5 minutes
Enabled single-operator workflow execution

Case 03

Reduced workflow failure rate from 20% → 1%

Redesigned automated workflow for robustness and usability.

An automated workflow was failing at a rate that threatened throughput and operator confidence. Re-architected the workflow for robustness and usability, eliminating the dominant failure modes.

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Outcomes

Workflow failure rate reduced from 20% to 1%
Improved operator usability and confidence
Sustained reliability at production volume

Case 04

Reduced late samples from 30% to 12%

Replaced paper-based workflow with real-time traceability.

A high-throughput CAP/CLIA clinical genomics lab tracked downstream lab processes on paper, creating fragmented visibility into sample status, reagent usage, and operator actions. Redesigned the workflow into system-enforced, real-time execution.

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Outcomes

Late samples reduced from ~30% to 12%
Eliminated extreme delays (>3 weeks)
Reduced external audit time from 5 days to 2.5 days

Case 05

Resolved clinical failures in a 1500+ sample run

Identified root cause and eliminated recurrence.

Diagnosed cross-system failure modes in a high-volume clinical run, traced root cause across assay, automation, and software layers, and implemented controls to prevent recurrence.

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Outcomes

Root cause identified across assay, automation, and software
Recurrence eliminated through targeted workflow controls
Restored confidence in clinical run reliability at scale

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